
Varo took a critical view of religion, rejecting the religious ideology of her childhood education, and instead hewed to the liberal and universalist ideas that her father instilled in her. Varo was given the basic education at a convent school that was typical for young ladies of a good upbringing at the time – but this experience fostered her rebellious tendencies. Romanesque and Gothic architecture, unique to Anglès, also showed up in her later artistic production. Those first few years of her life left an impression on Varo that would later show up as motifs in her work such as machinery, furnishings, and artifacts.

As she grew older, he provided her with texts on mysticism and philosophy. : 14 He encouraged independent thought and supplemented her education with science and adventure books, notably the novels of Alexandre Dumas, Jules Verne, and Edgar Allan Poe. Varo's father recognized her artistic talents early on and would have her copy the technical drawings of his work with their straight lines, radii, and perspectives, which she reproduced meticulously. Because of his work, the family moved to different locations across Spain and North Africa. Varo's father, Rodrigo Varo y Zajalvo (Cejalvo), was a hydraulic engineer.

She was the only girl, and the youngest of the three siblings. Varo would have two surviving siblings: an older brother Rodrigo, and another brother Luis. Her mother named her newborn in honor of the patron saint of Anglès, Virgen de los Remedios (the "Virgin of Remedies"), after a recently deceased older sister. Varo's mother, Ignacia Uranga Bergareche, had been born to Basque parents in Argentina she was a devout Roman Catholic. Remedios Varo Uranga was born in 1908 in Anglès, a small town in the province of Girona (Catalonia), in northeastern Spain. In the last thirteen years of her life she found financial stability in Mexico, painting productively until her sudden death in 1963. Varo had a difficult life, struggling against poverty and fleeing from war in Spain and then France.

María de los Remedios Alicia Rodriga Varo y Uranga (known as Remedios Varo, 16 December 1908 – 8 October 1963) was a Spanish-born Mexican : 18 surrealist painter working in Spain, France, and Mexico.
